and pharmacological properties of Kigelia africana (Lam.) Balmkheera, Isopinnatal, Kigelin, Chemical constituents, Medicinal properties. Objective: Kigelia africana, a tropical tree, which has long been used in African . Analytical grade solvents (Fischer chemicals) were used for isolation and. cancer with drugs (pharmacotherapy) or with chemical compounds ( chemotherapy) in family comprises 21 species, of which Kigelia africana. (Lam. ) Benth is.

Author: Grojar Dilkis
Country: Samoa
Language: English (Spanish)
Genre: Music
Published (Last): 24 January 2018
Pages: 273
PDF File Size: 14.89 Mb
ePub File Size: 8.13 Mb
ISBN: 136-8-63141-922-2
Downloads: 24491
Price: Free* [*Free Regsitration Required]
Uploader: Zolonos

The phytochemicals may be partly responsible for the biological activities observed for the leave of the plant when used in folkloric medicine.

Anti-inflammatory activity of verminoside from Kigelia africana and evaluation of cutaneous irritation in cell cultures and reconstituted human epidermis. Activity of Kigelia pinnata against melanoma and renal carcinoma cell lines.

The leaves were dried at room temperature and blended into powder. Fractions with similar TLC profile were combined and concentrated using the rotary evaporator. Monoterpenoids and naphthaquinone from Kigelia pinnata.

Chemical composition and antioxidant potentials of Kigelia pinnata root oil and extracts

Review in the studies on tannins activity of cancer prevention and anticancer. The same procedure has been followed for C-6 and C-7 carbons. Total antioxidant activity in plant materials and its interest in food technology. This activity may be connected with the antioxidant capability of the extract.

Royal Botanic Gardens, Kew, London, pp: Inhibition of carcinogenesis by dietary polyphenolic compounds. Niger J Nat Prod Med;1: Prediction of 1H NMR chemical shifts using neural networks.


Although an excess of Reactive Oxygen Species, ROS oxidative stress can result in non-controlled oxidation and damage of cellular structures such as DNA, protein and membrane lipids. Fetal growth in rats treated with lapachol.

The reducing capacity of the extracts, another significant indicator of antioxidant activity was also found to be appreciable. Aqueous extract of the bark of Kigelia africana reverses early testicular damage induced by methanol extract of Carica papaya.

Evaluation of antibacterial and antioxidant activity of leaves, fruit and bark of Kigelia africana. The mixture containing 2. J Health Biomed Sci. The antioxidant acivity was chemmicals using DPPH assay. Open in a separate window. The MS data are in agreement with literature data Golovnya et al. The antioxidant activity which correlated with the total phenolic content of the extracts was assumed to be from the total phenolic content of the extracts.

Chemical composition and antioxidant potentials of Kigelia pinnata root oil and extracts

An analysis by ABTS decolorization assay. Preparative thin layer chromatography was used for further purification and isolation of various compounds. Activity of extracts of Kigelia pinnata against melanoma and renal carcinoma cell lines. The sausage tree Kigelia pinnata: Identification of each component was carried out using the peak enrichment technique of reference compounds and as final confirmation of the peak identification by GC-MS, their spectral were compared with those of NIST library mass spectra.

None, Conflict of Interest: N Engl J Med.

In vitro antimicrobial screening of four reputed Bangladeshi medicinal plants. Combined fraction 25 and 26 indicated the beta-tocopherol II. How to cite this article: Amazingly, the three proton chemical shifts appeared as singlet each apparently due to the fact that each proton has no immediate neighbor for coupling.


The phytochemical analysis conducted on Kigelia pinnata extracts revealed the presence of tannins, flavonoids, steroids, phlobatannins, phenolics, anthraquinones, terpenoids and saponins.

Kigeelia and structure of two new dihydroisocoumarins from Kigelia pinnata. The relative percentages of the identified compounds are listed in Table 1. The remaining plant material was subsequently extracted with ethyl acetate for five days. Post-hoc test analysis was done using the Duncan multiple comparison test.

Numerous epidemiological studies have suggested a protective role of food polyphenols on human health Arts and Hollman, [ 5 ]. Bioactive compounds in nutrition and health-research methodologies for establishing biological function: TAA was found to be higher in methanol extract at 0.

It could serve as klgelia in the manufacture of a variety of food ingredients. The leaves of K. Antioxidant activities of Iranian Corn Silk. A leaf hydrocarbon from Syzygium jambos with stimulatory effects on the germination of Urediniospores of Puccinia psidii.

Samples and sample preparation: The antioxidant potential of the oil was compared to that of ethyl acetate and methanol extracts of the root. Oxidant and antioxidant signalling in plants: